Darrin Bast, Ph. Phone: ext. Other interests include pathogenic and host responses to other Gram positive organisms like Staphylococcus aureus and Streptococcus iniae. Studies in our laboratory employ both in vitro and in vivo techniques, including a novel murine model of pneumonia. Bast has presented numerous abstracts at both national and international conferences, and has published several papers in high-impact peer-reviewed infectious diseases journals including Infection and Immunity, Molecular Microbiology, Antimicrobial Agents and Chemotherapy, Journal of Antimicrobial Chemotherapy, New England Journal of Medicine and Clinical Infectious Diseases. He also has written a review article on Fluoroquinolone Resistance and a book chapter on Streptolysin S. In addition, he has refereed several articles for publication in the Journal of Antimicrobial Chemotherapy and Antimicrobial Agents and Chemotherapy. Lim S. Emerging Infectious Diseases 9:
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Group A streptococcus GAS is an important human pathogen that causes pharyngitis and invasive infections, including necrotizing fasciitis. We recently reported the discovery of a potential genetic determinant involved in SLS production, sagA, encoding a small peptide of 53 amino acids S. Betschel, S. Borgia, N. Barg, D. Low, and J. De Azavedo, Infect.